If you are able to get it work, great, glad to help. Confirm which version of NPP and plugins you have by looking at the Debug Info.Confirm whether using the menu version of the comment commands do what you expect, or not.Confirm whether the shortcuts you are typing match the shortcuts listed in the menu and shortcut mapper.(As did going to the Edit > Comment/Uncomment, and selecting each of the five entries.) I then changed to a different lanugage (Perl), which uses different comments, and it still did what I expected. Once 7.3.1 was installed I tried: File > New, Language > J > JavaScript, typed var a=1, then tried out the Ctrl-Q toggling, Ctrl-K multiple times to add multiple levels of single-line comment, Ctrl-Shift-K multiple times to clear them, and Ctrl-Shift-Q to use a block comment, and they all worked exactly as expected. Plugins : ComparePlugin.dll dbgpPlugin.dll mimeTools.dll NppConverter.dll NppExec.dll NppExport.dll NppFTP.dll NppTextFX.dll PluginManager.dll PythonScript.dll Path : C:\Program Files (x86)\Notepad++\notepad++.exe Looking at ? > Debug Info > Copy debug info into clipboard: Notepad++ v7.3.1 (32-bit) But when I noticed you claimed “latest version”, I finally download 7.3.1 (which still hasn’t auto-updated for me), and confirmed the same. And the Settings > Shortcut Mapper > Main menu entries agree. Are you sure you have the correct shortcuts? You said Alt-Q, but my Edit > Comment/Uncomment submenu shows Ctrl-Q on my installation, not Alt-Q.